GC-MS Analysis of Bioactive Compounds in Methanolic Extracts of Papaver decaisnei and Determination of Its Antioxidants and Anticancer Activities

The Papaver L. plant (Papaver decaisnei) has ethnobotanical records in many countries including Iraqi Kurdistan. current study investigates the methanol (99.9%) extracts (10 μg/mL) of roots, leaves, and flowers decaisnei terms phytochemistry by gas chromatography-mass spectrophotometry GC-MS, vitro antioxidant activity radical scavenging reducing power assays, finally, anticancer actions as IC50 (inhibitory concentration at 50%) against human colorectal adenocarcinoma (Caco-2), mammary cancer cells (MCF-7), cervical carcinoma (HeLa) cells. results showed 22, 19, 17 chemicals for P. decaisnei, respectively. prevalent organic compounds were alkaloids (62.03%), phenolics (55.43%), fatty acids (42.51%), esters (32.08%), terpenoids (25.59%), phytosterols (15.68%), namely, roemerine (70.44%), 9,12,15-octadecatrien-1-ol (37.45%), hexadecanoic acid (33.72%), decarbomethoxytabersonine (24.49%), γ-sitosterol (11.22%). organs was within 39.1–143.5 μg/mL DPPH, 135.4–276.4 ABTS, 12.4–34.3 FRAP, 42.6–75.8 CUPRAC assays. found 125.3–388.4 all tested cell lines (Caco-2, MCF-7, HeLa). detected bioactivity encourage future isolation those remarkable (reomerine) potential usage pharmaceutical industry.